1. Доктор Нихил Мунши. Специалист по множественной миеломе. Биография.

Dr. Nikhil Munshi, MD, explains the latest advances in blood cancer treatment. He is a professor at Harvard Medical School and Director at Dana Farber...

2. Множественная миелома: достижения и вызовы в терапии. Часть 1

Dr. Nikhil Munshi, MD, explains the remarkable progress in treating this complex blood cancer. He highlights key advances in genomic understanding, the tumor microenvironment, and...

3.

Множественная миелома

Генетические изменения

Моноклональная гаммапатия неопределенного значения (МГНЗ)

Вялотекущая миелома

Dr. Nikhil Munshi, MD, explains the key genetic changes that drive disease progression. He details how specific chromosomal abnormalities occur very early in MGUS and...

4. Множественная миелома и микроокружение костного мозга. Концепция «семени и почвы» в развитии онкологического заболевания. 3

Dr. Nikhil Munshi, MD, explains the critical role of the bone marrow microenvironment in cancer progression. He details the "seed and soil" concept where myeloma...

5. Множественная миелома и профилирование экспрессии генов. Внутриклональная гетерогенность. 4

Dr. Nikhil Munshi, MD, explains intraclonal heterogeneity. This is a core feature of cancer. Tumor cells acquire new genetic changes as they grow. This creates...

6. Множественная миелома. Критерии стратификации риска для подбора оптимальной терапии индивидуально для каждого пациента. 5

Dr. Nikhil Munshi, MD, explains how risk stratification guides treatment selection. He details the evolution of criteria from the Durie-Salmon system to modern cytogenetic and...

7. Аутологичная трансплантация стволовых клеток при множественной миеломе. 6

Dr. Nikhil Munshi, MD, explains how autologous stem cell transplantation remains a frontline therapy. He discusses the recent DFCI study results. Transplant provides a significant...

8. How to select drug combinations for multiple myeloma treatment? 7

Dr. Nikhil Munshi, MD, explains how treatment has evolved. He details the shift from two-drug to three and four-drug combinations. These new regimens achieve near...

9.

Терапия Т-клетками с химерным антигенным рецептором при множественной миеломе

Иммунотерапия CAR-T-клетками. 8

Dr. Nikhil Munshi, MD, explains how CAR T-cell therapy is revolutionizing treatment. He describes unprecedented response rates in late-stage patients.

10.

Множественная миелома

Оценка минимальной остаточной болезни

Прогноз

9

Dr. Nikhil Munshi, MD, explains how minimal residual disease (MRD) evaluation is a critical prognostic factor. He details the two state-of-the-art methods for MRD testing:...

11. Castleman Disease. Subtypes and treatment options. 10

Dr. Nikhil Munshi, MD, explains Castleman disease subtypes and treatment options. He details the differences between localized and multicentric forms of this rare lymphoproliferative disorder....

12. Future in multiple myeloma treatment. When will it be a ‘curable disease’? 11

Dr. Nikhil Munshi, MD, explains how a significant proportion of patients are effectively cured today. He discusses the evolution of treatment and the future role...

13. Множественная миелома. Часто задаваемые вопросы: Вакцинация, витамин D и здоровье костей, качество жизни. 12

Dr. Nikhil Munshi, MD, explains key patient concerns. He addresses COVID-19 vaccination and monoclonal antibody prophylaxis for immunocompromised patients.

14. Multiple myeloma. Patient’s story: elderly woman and ‘last hope’ CAR T-cell therapy. 13

Dr. Nikhil Munshi, MD, explains the power of novel treatments for relapsed disease. He shares a compelling patient story of an elderly woman who achieved...

15. Множественная миелома. Послание надежды в лечении онкологических заболеваний и в жизни. 14

Dr. Nikhil Munshi, MD, delivers a powerful message of hope for cancer patients. He explains that despite global challenges, incredible treatment advances provide numerous options....