1. Dr. Randy Cron. Pediatric rheumatology, Cytokine storm expert. Biography. 0
Dr. Randy Cron, MD, explains the critical nature of cytokine storm. He discusses its role in Multisystem Inflammatory Syndrome in Children (MIS-C) after COVID-19.
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2. Мультисистемный воспалительный синдром у детей (МВС-Д). Болезнь Кавасаки. Часть 1
Dr. Randy Cron, MD, explains how a cytokine storm causes Multisystem Inflammatory Syndrome in Children (MIS-C) after COVID-19. MIS-C is a rare but serious post-viral...
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3. Мультисистемный воспалительный синдром у детей (МВС-Д). Факторы риска.
Dr. Randy Cron, MD, explains the susceptibility factors for multisystem inflammatory syndrome in children (MIS-C). He details the surprising finding that previously healthy children are...
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4. Multisystem inflammatory syndrome in children. MIS-C. Prognosis and recovery. 3
Dr. Randy Cron, MD, explains the prognosis and recovery for children with Multisystem Inflammatory Syndrome (MIS-C). He details the typical hospital course, cardiac outcomes, and...
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5. Лечение цитокинового шторма. Часть 1. Причины:
COVID-19. CAR-T-клеточная терапия.
Dr. Randy Cron, MD, explains how the COVID-19 pandemic brought this life-threatening immune overreaction into common knowledge. He details the unique characteristics of the COVID-19...
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6. Лечение цитокинового шторма. Часть 2. Ингибиторы янус-киназ и кортикостероиды.
Dr. Randy Cron, MD, explains the role of JAK inhibitors and corticosteroids in treating severe COVID-19. He details how these immunomodulatory therapies work.
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7. Лечение цитокинового шторма. Часть 3. Ингибиторы ИЛ-6 и ИЛ-1. Анакинра. Тоцилизумаб. 6
Dr. Randy Cron, MD, explains the use of IL-1 and IL-6 inhibitors for treating severe COVID-19. He discusses the timing and sequencing of these biologic...
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8. Лечение цитокинового шторма. Часть 4. Стратегия «стабилизации воспаления». 7
Dr. Randy Cron, MD, explains the innovative 'inflammo-stabilization' treatment strategy. He details how targeting a single key cytokine can restore immune system balance during a...
Dr. Randy Cron, MD, explains the complex terminology and pathophysiology of macrophage activation syndrome (MAS). He details how MAS is a form of secondary hemophagocytic...
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10. Риск цитокинового шторма у госпитализированных пациентов с лихорадкой. Принцип диагностики «Бритва Оккама». 9
Dr. Randy Cron, MD, explains the diagnostic challenge of identifying cytokine storms in hospitalized patients with fever. He discusses why Occam's razor can be misleading...
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11. Цитокиновый шторм. Генетическая предрасположенность. Часть 1 из 10.
Dr. Randy Cron, MD, explains the genetic susceptibility to these life-threatening immune overreactions. He details the threshold model where partial genetic defects combine with triggers...
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12. Геномное секвенирование и предрасположенность к цитокиновому шторму. Часть 2. 11
Dr. Randy Cron, MD, explains how genomic sequencing identifies rare heterozygous mutations that increase susceptibility to severe inflammatory responses. He discusses the complex interpretation of...
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13. Перспективы детской ревматологии. Раннее назначение биологических препаратов вместо стратегии «лечение до достижения цели». 13
Dr. Randy Cron, MD, explains the future of treatment for children with rheumatic diseases. He discusses the shift from a traditional pyramid approach to an...
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14. Лечение ревматических заболеваний у детей. При выборе терапии используйте принцип «перевёрнутой пирамиды».
Dr. Randy Cron, MD, explains the paradigm shift in treating chronic rheumatic diseases in children. He advocates for a "reverse the pyramid" approach, starting with...
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15. Arthritis in children. FAQ. Nutrition in arthritis. Will my child outgrow arthritis? 15
Dr. Randy Cron, MD, explains the role of diet and nutrition in juvenile arthritis. He clarifies common misconceptions about children outgrowing juvenile idiopathic arthritis (JIA)....
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16. Pediatric arthritis FAQ. Can a child with arthritis lead a normal life? 16
Dr. Randy Cron, MD, explains how children with arthritis can lead normal lives. He discusses the shock of a juvenile arthritis diagnosis.
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17. История болезни. Цитокиновый шторм. Цитофагический гистиоцитарный панникулит. Возраст пациента: 17 лет.
Dr. Randy Cron, MD, explains a dramatic case of a teenage girl with cytophagic histiocytic panniculitis. She developed a life-threatening cytokine storm with multi-organ failure....
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18. Уроки пандемии COVID-19: верные и ошибочные прогнозы. 18
Dr. Randy Cron, MD, explains the most surprising lessons from the COVID-19 pandemic. He discusses his incorrect prediction about vaccine development and his correct prediction...
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19. Педиатрическая ревматология нуждается в улучшении организации. Ведущий специалист делится опытом. 19
Dr. Randy Cron, MD, explains the need for better organization in the subspecialty. He advocates for an early and aggressive treatment approach for rheumatic diseases...
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20. Современная педиатрическая ревматология: от прошлого к будущему. Достижения в терапии и смена парадигм за 20 лет.
Dr. Randy Cron, MD, explains how biologic agents have revolutionized treatment for juvenile idiopathic arthritis. He details the paradigm shift in care over the last...
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