Leading expert in multiple myeloma, Dr. Nikhil Munshi, MD, explains the critical role of the bone marrow microenvironment in cancer progression. He details the "seed and soil" concept where myeloma cells are the seed and the bone marrow is the soil. The microenvironment provides essential support for myeloma cell survival and growth. Modern therapies now target both the cancer cells and the surrounding microenvironment. Poisoning the soil makes it inhospitable for cancer growth. This dual approach significantly improves treatment efficacy.